To determine whether a single dose of Clindesse vaginal cream is comparable in efficacy and safety to Cleocin vaginal cream administered once daily for 7 days in the treatment of bacterial vaginosis.
Clindesse Cream, Extended Release
This multicenter, randomized, single-blind, parallel-group study enrolled patients with BV infections. Treatment consisted of sex a single intravaginal dose of Clindesse or 7 daily doses of Cleocin.
Efficacy clindesse safety were assessed days after the start of treatment. Resolution of individual Amsel's criteria was also evaluated.
Antibacterial treatment of bacterial vaginosis: current and emerging therapies
Treatment-emergent adverse events were monitored throughout the study. Ninety-five percent confidence intervals for each endpoint were consistent with equivalence between the clindesse products.
A single dose of Clindesse vaginal cream is equivalent in safety and efficacy sex a 7-dose regimen of Cleocin vaginal cream in the treatment of bacterial vaginosis. This represents a significant advance in the treatment of bacterial vaginosis.
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